Cellular target of UVB-induced DNA damage resulting in local suppression of contact hypersensitivity

article




Vink, A.A.

Shreedhar, V.

Roza, L.

Krutmann, J.

Kripke, M.L.
Experimental data are reviewed that lend support to the hypothesis that formation of DNA damage is the initiation event of local suppression of contact hypersensitivity (CHS) after exposure to ultraviolet (UV) radiaton and that the antigen-presenting cell (APC) is an important traget for this DNA damage. Chemicals/CAS: DNA, 9007-49-2
Topics





















Antigen-presenting cellsContact hypersensitivityDNA damagePhotoimmunologyUVBAntigen presenting cellConference paperContact allergyDNA damageImmunologyPriority journalUltraviolet b radiationAnimalsCells, CulturedDermatitis, ContactDNADNA DamageHumansImmunosuppressionModels, GeneticModels, ImmunologicalUltraviolet Rays
TNO Identifier
40641
Repository link
https://resolver.tno.nl/uuid:1b8faa61-7cb1-471f-bfa3-6d48eb00e4df
Source
Journal of Photochemistry and Photobiology B : Biology, 44, pp. 107-111.
Pages
107-111
Files
To receive the publication files, please send an e-mail request to TNO Repository.