Mixed lymphocyte reactivity in chimpanzees. II. Family studies and identification of D locus antigens

article

Jonker, M.

Balner, H.
A large number of related chimpanzees were tested in mixed lymphocyte cultures against each other. Several similarities among the D locus products coded for by different ChLA haplotypes were observed. Six animals were found to be homozygous for D locus antigens and two of these animals carried the same D specificity. Hence, the available 'typing cells' permitted the identification of five D locus antigens of the chimpanzee. So far, no linkage disequilibrium has been found between any of the D locus antigens and ChLA-A or -B locus antigens. Chemicals/CAS: Epitopes; Histocompatibility Antigens
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HeredityIn vitro studyMajor histocompatibility complexMixed lymphocyte reactionMonkeyAnimalChromosome MappingEpitopesFemaleGenotypeHaploidyHistocompatibility AntigensHomozygoteLinkage (Genetics)Lymphocyte Culture Test, MixedMalePan troglodytes
TNO Identifier
229044
Repository link
https://resolver.tno.nl/uuid:098ab04e-d781-4f3f-ac6f-15f6df9c0390
ISSN
0001-2815
Source
Tissue Antigens, 17(2), pp. 179-194.
Pages
179-194
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