A review : Current knowledge of the D/DR region of the major histocompatibility complex of rhesus monkeys and chimpanzees
article
Although the long-established series of International Histocompatibility Workshops and Symposia has always primarily been concerned with human tissue typing, it has become a tradition to include brief reports also on the state of tissue typing in chimpanzees and/or rhesus monkeys. The principal subjects of this Eighth Workshop are clearly the D and DR locus antigens of man. To our knowledge, the rhesus monkey and chimpanzee are, beside man, the only outbred species in which D and DR antigens have been studied and compared. Hence it may be appropriate to focus our attention in this short review also on that subject. We start with data available for rhesus monkeys, a species for which the knowledge of MHC-controlled antigens is about equally advanced as that for man, and subsequently summarize the still rather scanty data on D and DR antigens of the chimpanzee. Chemicals/CAS: Epitopes; Histocompatibility Antigens Class II; Histocompatibility Antigens
Topics
apeblood and hemopoietic systemheredityHLA systemlymphatic systemchromosome mapgenetic linkagegeneticsimmunologymixed lymphocyte culturephenotypereviewRNA translationepitopehistocompatibility antigenHLA antigen class 2AnimalChromosome MappingEpitopesHistocompatibility AntigensHistocompatibility Antigens Class IILinkage (Genetics)Lymphocyte Culture Test, MixedMacacaMacaca mulattaMajor Histocompatibility ComplexPan troglodytesPhenotypeTranslation, Genetic
TNO Identifier
228906
ISSN
01988859
Source
Human Immunology, 1(4), pp. 305-316.
Pages
305-316
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