Normal values for the urinary excretion of some 17-oxosteroids and pregnanediols in healthy male adolescents
article
In urine samples of 52 male adolescents the excretion values were determined for seven 17-oxosteroids as well as for pregnanediol and allopregnanediol. The data were classified according to chronological age and skeletal age. The age dependency for the different steroid excretions differs considerably, ranging from practically no increase for the pregnanediols to a rapid increase for the androgens. Though the androgen excretions level off at the age of sixteen, a considerable increase after puberty can still be expected. In general, the androsterone excretion exceeded the etiocholanolone excretion, a fact which became even more pronounced with increasing age. The 11-deoxysteroids to 11-oxosteroids ratio showed a very sharp increase at the beginning of puberty. Hydrolysis procedure and results were discussed against the background of comparable data from the literature. © 1973.
Chemicals/CAS: androsterone, 53-41-8; etiocholanolone, 53-42-9; prasterone, 53-43-0; pregnanediol, 26445-07-8, 80-92-2; 11-Hydroxycorticosteroids; Androsterone, 53-41-8; Etiocholanolone, 53-42-9; Prasterone, 53-43-0; Pregnanediol, 26445-07-8
Chemicals/CAS: androsterone, 53-41-8; etiocholanolone, 53-42-9; prasterone, 53-43-0; pregnanediol, 26445-07-8, 80-92-2; 11-Hydroxycorticosteroids; Androsterone, 53-41-8; Etiocholanolone, 53-42-9; Prasterone, 53-43-0; Pregnanediol, 26445-07-8
Topics
TNO Identifier
280788
ISSN
00098981
Source
Clinica Chimica Acta, 44(3), pp. 307-318.
Pages
307-318
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