Pathophysiology of ageing in animal models
bookPart
One of the main goals of experimental ageing research is to understand the mechanisms of ageing in order rationally to approach the health problems of the aged as well as to increase the quality of life in this phase of human existence. In addition to studies in man, animal models are needed to understand the physiology and pathophysiology of ageing in organs and organ systems. With regard to the question of extrapolation of data from animals to man, we have to realise that the fundamental aspects of the ageing process are the same in all mammals. It has to be considered that, as in man, the diseases occurring at old age in animals are superimposed on the normal physiological deterioration. These age-associated physiological deteriorations certainly increase susceptibility to disease, but should be studied apart from diseases occurring in old age. © 1979 Editors
TNO Identifier
355606
Publisher
Palgrave MacMillan
Source title
Drugs in the elderly elderly : Perspectives in geriatric clinical pharmacology, Proceedings Symp. Ninewells Hospital, Univ. of Dundee, 13-14 September 1977
Editor(s)
Crooks J., Stevenson I.H.
Place of publication
London
Pages
15-22
Files
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