Longevity studies in rhesus monkeys after X-ray and neutron irradiation with special emphasis on tumour induction
conference paper
Over the past 15 years experiments have been performed on the mortality of rhesus monkeys and the effects of bone marrow transplantation after irradiation with X-rays and fission neutrons. It had been previously established that, for neutrons as well as for X-rays, bone marrow transplantation was effective in protecting the animals from death due to the haemopoietic syndrome. Of the group of X-irradiated monkeys, 14 survived more than three years after irradiation, whereas in the neutron-irradiated group nine animals were long-term survivors. A control group of comparable age distribution comprises a total number of 13 non-treated rhesus monkeys. All animals are kept under continuous observation to study the late effects of radiation. After latent periods of 4 to 12 years, five neutron-irradiated and one X-irradiated animal died with tumours. The relation between the latency period, the radiation dose and the types and localizaton of tumours are discussed. The present results suggest relatively high effectiveness of fission neutrons for tumour induction.
TNO Identifier
355065
ISBN
9200107788, 9789200107788
Publisher
International Atomic Energy Agency
Source title
Symposium on the Late Biological Effects of Ionizing Radiation, 1978 March 13-17, Vienna, Vol II
Place of publication
Vienna
Pages
165-179
Files
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