Determination of the colonization resistance of the digestive tract of individual mice

article

Waaij, D. van der

Berghuis, J.M.
It has been shown that it is possible to investigate the colonization resistance in individual mice by determining the concentration of a certain contaminant (S.R. E. coli) in the faeces during the first 4 days after contamination. Experimental contamination is contra indicated in many cases such as in individuals with decreased resistance to infection. Particularly in this group, the value of the colonization resistance should be determined. It appeared to be possible to determine the colonization resistance in such individuals by quantitative biotyping of the Enterobacteriaceae species in the faeces on several consecutive days.
Chemicals/CAS: Bacitracin, 1405-87-4; Natamycin, 7681-93-8; Neomycin, 1404-04-2; Streptomycin, 57-92-1
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escherichia coliIntestinal colonization resistanceIntestine floraTheoretical studyAdministration, OralAnimalBacitracinBacteriaBiological AssayEnterobacteriaceaeEscherichia coliFecesFemaleIntestinesMiceNatamycinNeomycinRadiation EffectsStreptomycin
TNO Identifier
227699
Repository link
https://resolver.tno.nl/uuid:a39ff5bb-f360-4e84-9525-923798159b71
ISSN
00221724
Source
Journal of Hygiene, 72(3), pp. 379-387.
Pages
379-387
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