Fibrinolytic activity in protein S deficiency
article
In recent years, it has been established that a hereditary deficiency of protein S is associated with an increased risk of venous thrombosis. Among and within protein S deficient families however, the clinical expression of the deficiency is variable. Protein S deficient individuals may develop thrombosis or they may remain asymptomatic for a long time, despite the fact that they might have experienced a number of risk situations such as trauma, surgery, pregnancy etc. (1). Additional factors might therefore be involved in determining the clinical expression of protein S deficiency. We studied whether variations in fibrinolysis, especially in the t-PA/PAI system, might be related to the variation in clinical presentation of protein S deficiency.
Chemicals/CAS: plasminogen activator inhibitor, 105844-41-5; tissue plasminogen activator, 105913-11-9
Chemicals/CAS: plasminogen activator inhibitor, 105844-41-5; tissue plasminogen activator, 105913-11-9
Topics
TNO Identifier
230547
ISSN
02689499
Source
Fibrinolysis, 2(2 Suppl.), pp. 55-56.
Pages
55-56
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