LC50 estimates and their confidence intervals derived for tests with only one concentration with partial effect
article
Linear approximation fails to determine the likelihood based confidence interval for the LC50 parameter in a toxicity experiment with only one concentration causing partial mortality. An equation for this confidence interval is derived given a log-logistic concentration response relation. A table of the 95 and 99% confidence intervals is given for the case that partial survival occurs only at one concentration, under the condition that a fixed number of animals is used at each test concentration and a constant ratio is used between the test concentrations.
TNO Identifier
231532
ISSN
00431354
Source
Water Research, 25(4), pp. 401-408.
Pages
401-408
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