Isolation of infectious C type oncornavirus from human leukaemic bone marrow cells

article


Nooter, K.

Aarssen, A.M.

Bentvelzen, P.
The authors report the isolation of a C type oncornavirus from a 4 yr old patient with a lynphosarcoma which had progressed to a state of lymphoblastic leukemia. Bone marrow cells were cultured in liquid suspension in the presence of phytohemagglutinin. After 3 days culture, the supernatant was examined for the presence of C type particles using the Millipore filter technique and was found to be positive.
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bone marrow cellcell culturecytopathogenic effectelectron microscopyetiologyin vitro studyleukemialeukemia virusleukovirusmethodologymicroorganismoncovirinaetheoretical studyvirologyvirusvirus infectionvirus isolationvirus particleBone MarrowBone Marrow CellsChild, PreschoolHumanLeukemia, LymphocyticMicroscopy, ElectronRetroviridae
TNO Identifier
227931
Repository link
https://resolver.tno.nl/uuid:b4913d30-d88f-431c-bb92-077ebe510d6a
ISSN
00280836
Source
Nature, 256(5518), pp. 595-597.
Pages
595-597
Files
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