The effect of differing concentrations of SnF2 on demineralized enamel
article
The effect of different concentrations of stannous fluoride (SnF2) on demineralized enamel was studied, on cross-sections, using microhardness and densitometric measurements. SnF2 solutions, ranging in concentration from 0.5 to 8%, were applied to artificially demineralized enamel surfaces. It was found that the hardness increase in the surface layer was similar in all groups but that the radiodensity increased significantly with increasing concentration. It is suggested that these results are due to the maximum formation of fluorapatite from the available brushite, thus improving the crystalline structure and giving equal hardness in all groups, whilst the increase in radiodensity demonstrates the incorporation of stannous ions resulting in an increase in mineralization. In the subsurface lesion there was an increase in hardness with increasing concentration. This trend was also seen in the microradiographic results but to a much greater degree. This more demineralized area requires a greater SnF2 influx for the formation of stannous compounds which appear primarily to have a space-filling and mineralizing function. It can be concluded that: maximum surface rehardening occurred after the application of an 0.5% SnF2 solution; maximum increase in hardness and radiodensity in both the surface layer and subsurface lesion occurred after the application of an 8% SnF2 solution; hardness increases are not directly correlated to the increase in radiodensity.
Chemicals/CAS: tin fluoride, 55128-73-9, 67339-76-8; Fluorides; Minerals; Tin Fluorides
Chemicals/CAS: tin fluoride, 55128-73-9, 67339-76-8; Fluorides; Minerals; Tin Fluorides
Topics
radioisotopetin fluoridedemineralizationdose responsedrug analysisdrug efficacyenamelhumanin vitro studylichen sclerosus et atrophicusmethodologymineralizationnormal humanradioimmunoassayradiopacityremineralizationtheoretical studyComparative StudyDensitometryDental EnamelFluoridesHardnessHumanMineralsTemperatureTin Fluorides
TNO Identifier
228358
ISSN
00086568
Source
Caries Research, 12(1), pp. 43-51.
Pages
43-51
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