Safe-and-Sustainable-by-Design Approach and Decision Support System for Advanced Materials
article
To facilitate Safe-and-Sustainable-by-Design (SSbD), the HARMLESS project developed a practical SSbD approach and SSbD Decision Support System (DSS) for advanced materials. The HARMLESS SSbD approach and SSbD-DSS are in alignment with the EU-recommended SSbD framework and methods. The HARMLESS SSbD approach recommends New Approach Methodologies (NAMs) tailored to advanced materials and the innovation stage of the material under development. The approach follows a flexible stage-gate model with three innovation stages: 1) Ideation & Business Case Phase, 2) Lab Phase, and 3) Pilot Phase. The HARMLESS SSbD-DSS guides designers through a workflow starting with the Advanced Material Earliest Assessment (AMEA) tool. AMEA contains three questions enabling categorization and subsequently advice on design principles. A second tool, named Warning flags, Design Advice, Screening Priorities (WASP), consists of 12 questions to identify early warning flags and provide design and assessment advice. A third tool, named Alternative SSbD Design Inspector (ASDI), provides guidance on descriptors to measure in the Lab Phase for informed decision making on the most optimal SSbD version. By adapting the data and resource requirements to each innovation stage, the SSbD-DSS facilitates practical implementation of SSbD, supporting the user to find a transparent balance between safety, sustainability, and performance. © 2025 The Author(s). Advanced Sustainable Systems published by Wiley-VCH GmbH.
TNO Identifier
1018027
Source
Advanced Sustainable Systems, pp. e00208.
Pages
e00208