Apolipoprotein E polymorphisms and the genetic heterogeneity of familial dysbetalipoproteinemia
bookPart
Chylomicrons are secreted from the intestine into the lymph, whereafter they enter the bloodstream. In the bloodstream these particles are partly lipolyzed by lipoprotein lipase (LPL) and the chylomicron-remnant particles just formed are rapidly taken up by hepatic lipoprotein receptors. The liver secretes VLDL particles and, similar to chylomicrons in the bloodstream, VLDLs are partly lipolyzed by LPL and the VLDLremnants or IDL particles formed are taken up with high affinity by the hepatic LDL receptors.
TNO Identifier
268143
ISBN
978-1-4613-6640-9
Publisher
Springer
Source title
DNA polymorphisms as disease markers
Editor(s)
Galton, D.J.
Asmann, G.
Asmann, G.
Place of publication
Boston
Pages
71-77
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