Effects of a moderate dose of alcohol on blood lipids and lipoproteins postprandially and in the fasting state
article
Effects of a moderate dose of alcohol on blood lipids and lipoproteins were studied in volunteers of two age groups(20-30 and 45-55 years), each consisting of eight healthy men. The alcohol (30 g in red port and wine) was consumed during a standard dinner. Two blood samples were drawn: one in the postprandial phase, and one the next morning after fasting overnight. In the postprandial phase, one hour after intake, alcohol increased high-density lipoprotein cholesterol (HDL-C) by 11.5%, triglycerides (TG) by 15.3% and apolipoprotein A2(Apo-A2) by 7.3% (P= 0.002, P=0.044 and P= 0.024, respectively). The increase in HDL-C appeared to be mainly attributed to the HDL2-C subfraction which increased by 15.3% (P= 0.066).Futhermore, the increases in HDL-C, HDL2-C and TG were more pronounced in the middle-aged men then in the young men. After fasting overnight the effects of alcohol had disappeared.
Chemicals/CAS: Apolipoprotein A-II; Apolipoproteins A; Dietary Fats; Dietary Proteins; Ethanol, 64-17-5; Lipids; Lipoproteins; Lipoproteins, HDL Cholesterol; Triglycerides
Chemicals/CAS: Apolipoprotein A-II; Apolipoproteins A; Dietary Fats; Dietary Proteins; Ethanol, 64-17-5; Lipids; Lipoproteins; Lipoproteins, HDL Cholesterol; Triglycerides
Topics
TNO Identifier
231220
ISSN
07350414
Source
Alcohol and Alcoholism, 25(4), pp. 371-377.
Pages
371-377
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