Double-blind study of leucocyte interferon administration in chronic HBsAg-positive hepatitis
article
In a double-blind study human leucocyte interferon was given for six weeks to 8 of 16 patients with chronic HBsAg-positive hepatitis. In the first week 12×106 reference units were administered daily, and thereafter the dose was halved every week. During the first two weeks leucopenia was observed in 6 of the 8 interferon-treated patients. Apart from a drop in DNA-polymerase activity in the first week, no effect was found on indices of hepatitis-B-virus infection.
TNO Identifier
355910
Source
The Lancet, 315(8164), pp. 336-338.
Pages
336-338
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