Determination of nucleosides and their adducts with RP-HPLC and (laser-)fluorescence detection
article
The labelling method presented here is based on the derivatization of nucleosides with 1-anthroylnitril in the presence of quincuclidine. This method is introduced by Goto et al. [8-13] for the determination of steroids, like 6β-hydroxycortisol and serum bile acids. This paper mainly deals with the use of 1-anthroylnitril for the derivatization of nucleosides, followed by separation with RP-HPLC and quantification with (laser-)fluorescence detection.
TNO Identifier
231223
ISSN
07328311
Source
Nucleosides and Nucleotides, 9(3), pp. 395-405.
Pages
395-405
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