Massive pericellular collagen deposition in the liver of a young female with severe Crohn's disease

article



Bosma, A.

Meuwissen, S.G.

Stricker, B.H.

Brouwer, A.
We report a patient with Crohn's disease in whom repeated liver biopsies taken at surgery for the bowel disease showed progressive hepatic fibrosis of an unusual type. Dense collagen was deposited in the perisinusoidal space often surrounding individual hepatocytes. The aetiology and pathogenesis of this abnormality remain speculative.
Chemicals/CAS: alcohol, 64-17-5; collagen, 9007-34-5; Collagen, 9007-34-5
Topics



















alcoholcollagenadultcase reportcrohn diseasefemalehistologyhumanhuman cellliver fibrosisliver sinusoidpriority journalAdultCase ReportCollagenCrohn DiseaseFemaleHumanLiverLiver Cirrhosis
TNO Identifier
230844
Repository link
https://resolver.tno.nl/uuid:f435b1a0-f6a4-4a3f-a313-f2f2e3c774db
ISSN
03090167
Source
Histopathology, 14(1), pp. 81-90.
Pages
81-90
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