High incidence of spontaneous cervical and vaginal tumors in an inbred strain of brown Norway rats (BN/Bi)

article


Burek, J.D.

Zurcher, C.

Hollander, C.F.
The incidence of spontaneously occurring tumors of the cervix and vagina was unusually high in an inbred strain of Brown Norway rats (BN/Bi). 54 Tumors were diagnosed in the cervixes or vaginas of 252 rats. Of the tumors, 7 were squamous cell carcinomas, 4 were leiomyomas, and the rest were sarcomas. These tumors were found in nearly 20% of all female rats that died naturally.
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diagnosisetiologygeneticshistologyinbreedingmodelraceratuterine cervix cancervagina cancerAnimalCervix NeoplasmsFemaleRatsRats, Inbred BNRats, Inbred StrainsRodent DiseasesVaginal Neoplasms
TNO Identifier
228086
Repository link
https://resolver.tno.nl/uuid:1b5e52d8-cbeb-4509-87ab-5b9b0f663457
ISSN
00278874
Source
Journal of the National Cancer Institute, 57(3), pp. 549-554.
Pages
549-554
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