Protocol for X-ray dosimetry and exposure arrangements employed in studies of late somatic effects in mammals

article






Zoetelief, J.

Davies, R.W.

Scarpa, G.

Hofmeester, G.H.

Dixon-Brown, A.

Kogel, A.J. vander

Broerse, J.J.
A number of European laboratories studying the late effects of ionizing radiation in animals have established an effective cooperation within the European Late Effects Project Group (EULEP) since 1970. To facilitate the exchange of biological results several techniques, including quality control of the experimental animals, pathology and dosimetry, have to be standardized. The most important aspects of the procedures for X-irradiation and dosimetry of small animals are summarized. These include recommendations on irradiation conditions, dosimetry methods, characteristics of phantoms and factors affecting X-ray dosimetry. X-irradiation procedures employed by the participating institutes are described and the results of five X-ray dosimetry intercomparisons are reported. The introduction of a common dosimetry protocol has resulted in improvements in exposure arrangements and absolute dosimetry.
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animal experimentdosimetrymammalmethodologynonhumanpriority journalradiation exposureradiobiologyreviewX rayAnimalAnimals, LaboratoryComparative StudyMiceModels, StructuralRadiation DosageRadiobiologyRadiometryRatsSupport, Non-U.S. Gov'tTime FactorsWhole-Body Irradiation
TNO Identifier
229780
Repository link
https://resolver.tno.nl/uuid:6def1d94-568f-4d6b-9598-e994759b8bad
ISSN
09553002
Source
International Journal of Radiation Biology, 47(1), pp. 81-102.
Pages
81-102
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