The major histocompatibility complex of rhesus monkeys. XIV. A family study of DR and other RhLA-linked cell membrane antigens

article


Balner, H.

Vreeswijk, W. van

Roger, J.H.
The segregation of B-cell specific (Ia) determinants was studied in a large number of rhesus families. As expected, on the basis of results of a recent population study, the eight serologically defined DR antigens segregated as alleles of a single locus within RhLA. Two or three antigens not controlled by DR remained candidates for a second Ia series closely linked to DR. The 162 identifiable haplotypes provided interesting information regarding positive associations among antigens of two, three or even four sets of RhLA loci. Further, a new series of antigens closely linked to the RhLA-A locus could be postulated. Data obtained from 8 recombinant off-spring permitted a better definition of the mapping position of all known loci of RhLA. Chemicals/CAS: Antigens, Surface; Histocompatibility Antigens Class II; Histocompatibility Antigens
Topics
















membrane antigenanimal experimentblood and hemopoietic systemhereditymajor histocompatibility complexmonkeyAnimalAntigens, SurfaceChromosome MappingFemaleGenes, StructuralHistocompatibility AntigensHistocompatibility Antigens Class IIMacacaMacaca mulattaMajor Histocompatibility ComplexMale
TNO Identifier
229154
Repository link
https://resolver.tno.nl/uuid:29a15733-b615-43c3-98b1-10a941f6c438
ISSN
0001-2815
Source
Tissue Antigens, 17(5), pp. 530-539.
Pages
530-539
Files
To receive the publication files, please send an e-mail request to TNO Repository.