Selective decontamination of the digestive tract of Syrian hamsters

article



Angulo, A.F.

Spaans, J.

Zemmouchi, L.

Waaij, D. van der
Conventional Syrian hamsters colonized with aerobic gram-negative bacteria such as Pasteurella pneumotropica and various Enterobacteriaceae species were successfully and permanently freed from these microorganisms by oral treatment for 4 weeks with dihydrostreptomycin and 'Orabase' premixed with appropriate antibiotics. Concomitant oral treatment with dimetridazol for the elimination of intestinal flagellates was unsuccessful. During treatment the animals were maintained under germ-free isolation conditions.
Chemicals/CAS: dihydrostreptomycin, 128-46-1, 5490-27-7; Dihydrostreptomycin Sulfate, 5490-27-7; Dimetridazole, 551-92-8; Neomycin, 1404-04-2
Topics

















dihydrostreptomycinanimal experimentdigestive systemgastrointestinal tractmicroflorawaste managementAnimalDihydrostreptomycin SulfateDimetridazoleEnterobacteriaceaeGastrointestinal SystemGerm-Free LifeHamstersIntestinesMastigophoraMesocricetusNeomycinPseudomonas
TNO Identifier
228421
Repository link
https://resolver.tno.nl/uuid:c5e838a3-387b-44e3-97e7-39977bf59e6b
ISSN
00236772
Source
Laboratory Animals, 12(3), pp. 157-158.
Pages
157-158
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