Dose-response relationships regarding vitamin B-6 in elderly people: A nationwide nutritional survey (Dutch nutritional surveillance system)
article
The dietary intake and biochemical status of vitamin B-6 in 476 apparently healthy Dutch elderly people (aged 65-79 y), who were not using drugs known to affect vitamin B-6 metabolism, were evaluated. Intake of vitamin B-6 per gram protein was related to biochemical data, namely plasma pyridoxal 5'-phosphate (PLP) and cofactor stimulation of aspartate aminotransferase in erythrocytes (AST-AC). Based on a cutoff point of 2.02 for AST-AC, ~9% of the elderly people not using vitamin B-6 supplements had a marginal vitamin B-6 status. About 7% were using vitamin B-6 supplements. Dietary intake of vitamin B-6 per gram protein was negatively related to AST-AC. Vitamin B-6 intakes per gram protein higher than 0.020 mg were necessary to ensure an AST-AC value < 2.02. At high PLP values AST-AC hardly varied. The results seem to indicate a higher requirement of vitamin B-6 in elderly people than in younger adults.
Chemicals/CAS: pyridoxine, 12001-77-3, 58-56-0, 65-23-6, 8059-24-3; Aspartate Aminotransferases, EC 2.6.1.1; Pyridoxal Phosphate, 54-47-7; Pyridoxine, 65-23-6
Chemicals/CAS: pyridoxine, 12001-77-3, 58-56-0, 65-23-6, 8059-24-3; Aspartate Aminotransferases, EC 2.6.1.1; Pyridoxal Phosphate, 54-47-7; Pyridoxine, 65-23-6
Topics
TNO Identifier
230825
ISSN
00029165
Source
American Journal of Clinical Nutrition, 50(2), pp. 391-399.
Pages
391-399
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