ISI values and interhemispheric differences in patients with ischemic cerebrovascular disease; correlations with clinical and angiographic findings
article
Xenon 133 inhalation CBF studies of one hundred patients with ischemic cerebrovascular disease in the territory of the carotid artery were compared in an attempt to gain more insight into the collateral capacity, especially in those with a stenosis or occlusion of one of the major arteries. Asymmetry of the ISI values for the two hemispheres was expressed as a ratio. High ratios (greater ISI asymmetries) were found for patients with an occlusion of the internal carotid or middle cerebral artery, especially - but not exclusively - those with the more severe clinical symptoms. It also appeared that even when the patient is in a good clinical condition, an elevated ratio reflects insufficiency of the collateral supply to the affected side. The ISI values for individual patients seem to be less useful, partly due to the variable age dependency of this flow parameter.
Chemicals/CAS: xenon 133, 14932-42-4; Xenon Radioisotopes
Chemicals/CAS: xenon 133, 14932-42-4; Xenon Radioisotopes
Topics
RadioisotopeXenon 133Brain angiographyBrain blood flowCentral nervous systemComputer analysisDiagnosisEtiologyHemisphereMajor clinical studyPeripheral vascular systemStrokeTransient ischemic attackAdolescentAdultAge FactorsAgedBlood PressureBrain IschemiaCerebral AngiographyHumanMiddle AgeSupport, Non-U.S. Gov'tXenon Radioisotopes
TNO Identifier
280696
ISSN
00392499
Source
Stroke, 17(1), pp. 58-64.
Pages
58-64
Files
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