The clonal culture in vitro of multipotential hemopoietic cells : Problems and interpretations

article
Metcalf, D.
The ability to clone mixed hemopoietic colonies in vitro now permits hemopoietic populations to be more effectively assayed for multipotential precursor cells but it is unclear whether all CFU-S are detectable by the culture systems in current use. From the available data, some caution should be used in assuming that the in vitro culture systems give a direct estimate of the repopulating capacity of the population. Although the factors stimulating mixed colony formation have not been purified, it is now possible to analyze the early cellular events during commitment to specific hemopoietic lineages.
Chemicals/CAS: Colony-Stimulating Factors; Culture Media
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blood and hemopoietic systemcloningcolony forming unithematopoiesislymphatic systemreviewAgingAnimalCells, CulturedClone CellsColony-Stimulating FactorsCulture MediaHematopoietic Stem CellsHumanMiceMice, Inbred StrainsSupport, Non-U.S. Gov'tSupport, U.S. Gov't, P.H.S.
TNO Identifier
228975
Repository link
https://resolver.tno.nl/uuid:484d3456-5b7c-4d91-81bb-c9a4057f0e91
ISSN
00294810
Source
Nouvelle Revue Francaise d'Hematologie, 23(3), pp. 165-169.
Pages
165-169
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