A patient with a VEGF and endostatin producing gastrointestinal autonomic nerve tumour

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Hansma, A.H.G.

Hensbergen, Y. van

Kuenen, B.C.

Diest, P.J. van

Hanemaaijer, R.

Meijer, S.

Pinedo, H.M.

Hoekman, K.
Tumour associated neovascularisation has been characterised as chaotic and insufficient. This report details the results of the analysis of angiogenic factors in tumour cyst fluid, pleural fluid, and blood from a patient with a gastrointestinal autonomic nerve tumour. The tumour produced vascular endothelial growth factor and endostatin in large quantities, which may explain the dysfunctional angiogenesis and tendency to bleeding seen in this tumour type. Chemicals / CAS: endostatin, 187888-07-9; vasculotropin, 127464-60-2; Endostatins; Neoplasm Proteins; Vascular Endothelial Growth Factor A
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Biomedical Researchangiogenic factorendostatinvasculotropinangiogenesisautonomic neuropathycase reportclinical featuregastrointestinal autonomic nerve tumorhuman tissuelaparotomyliver hemorrhagelung metastasispleurodesispriority journalprotein secretiontumor volumeAdultAutonomic Nervous System DiseasesEndostatinsFemaleGastrointestinal NeoplasmsHumansNeoplasm ProteinsNeovascularization, PathologicPeripheral Nervous System NeoplasmsVascular Endothelial Growth Factor A
TNO Identifier
237751
Repository link
ISSN
00219746
Source
Journal of Clinical Pathology, 57(5), pp. 536-538.
Pages
536-538
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