The reproducibility of the conversion of nitrate to nitrite in human saliva after a nitrate load

article



Bos, P.M.J.

Brandt, P.A. van den

Wedel, M.

Ockhuizen, T.
We investigated the reproducibility of the inter- and intra-individual variations in the conversion of nitrate to nitrite in saliva. Saliva samples were collected from 20 volunteers just before and at regular intervals after a nitrate load on four non-consecutive days within a period of 2 months. On three occasions beetroot juice was the nitrate source and on one occasion a nitrate solution was given. Despite large day-to-day variations it was possible to discriminate between subjects with a consistently high or low nitrate conversion after a nitrate load. Neither saliva sampling before a nitrate load nor single saliva samples are sufficient to obtain clear information about individual capacities for nitrate-nitrite conversion.
Chemicals/CAS: nitrate, 14797-55-8; nitrite, 14797-65-0; Ascorbic Acid, 50-81-7; Nitrates; Nitrites; Vitamin E, 1406-18-4
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nitratenitriteadultfemalehumanhuman experimentmalenormal humansalivaAscorbic AcidHumanNitratesNitritesPilot ProjectsSalivaSmokingSupport, Non-U.S. Gov'tVitamin E
TNO Identifier
230644
Repository link
https://resolver.tno.nl/uuid:84260559-ad9d-43e1-8bf8-82d4de59628f
ISSN
02786915
Source
Food and Chemical Toxicology, 26(2), pp. 93-97.
Pages
93-97
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