Bile acids, neutral steroids, and bacteria in feces as affected by a mixed, a lacto-ovovegetarian, and a vegan diet

article





Faassen, A. van

Bol, J.

Dokkum, W. van

Pikaar, N.A.

Ockhuizen, T.

Hermus, R.J.J.
In a metabolic ward 12 healthy male subjects consumed mixed Western (M), lacto-ovovegetarian (L), and vegan (V) diets in a randomized order for 20 d each. The concentrations of deoxycholic acid, isolithocholic acid, and total bile acids in 4-d composites of feces on the L and V diets were significantly lower than on the M diet. The chenodeoxycholic-to-isolithocholic plus lithocholic acid ratio was significantly higher on the V diet. The concentrations of coprostanol and of coprostanol plus cholesterol were highest on M diet and lowest on V diet. The number of fecal lactobacilli and enterococci on the V diet was significantly lower than on the M or the L diets. This study showed a decrease in the concentration of fecal (secondary) bile acids by the L and the V diets and an alteration of the fecal flora composition by the V diet.
Chemicals/CAS: chenodeoxycholic acid, 474-25-9; cholesterol, 57-88-5; deoxycholic acid, 83-44-3; Bile Acids and Salts; Cholestanol, 80-97-7; Cholesterol, 57-88-5; Deoxycholic Acid, 83-44-3; Lithocholic Acid, 434-13-9; sitosterol, 5779-62-4; Sitosterols; Steroids
Topics

































bile acidchenodeoxycholic acidcholesteroldeoxycholic acidsteroidcolorectal cancercoprastanoldietenterococcusepidemiologyfeces microflorahumanhuman experimentisolithocholic acidlactobacilluslactovegetarianmicroorganismveganismAdultAnimalBacteriaBile Acids and SaltsCholestanolCholesterolDeoxycholic AcidDiet, VegetarianEggsFecesHumanLithocholic AcidMaleMilkSitosterolsSteroids
TNO Identifier
230467
Repository link
https://resolver.tno.nl/uuid:1f462aee-8e9a-4e55-a9b2-678d7ff9d6ac
ISSN
00029165
Source
American Journal of Clinical Nutrition, 46(6), pp. 962-967.
Pages
962-967
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