In vitro investigation of the biological effects associated with human lung cells exposed to several indoor air sources
conference paper
In the last decade, studies on indoor air pollution suggest a link between exposure to indoor particulate matter (PM), and compounds, in particular ultrafine particles (UFP) and secondary organic aerosols (SOA), and several health effects. The mechanisms of how those complex mixtures relate to health effects are still not fully understood. In vitro testing, i.e. performing a given procedure in a controlled environment outside of a living organism, provides an additional source of information next to the exposure of persons or animals to controlled environmental conditions in a laboratory environment. Possible end-points that can be determined with such a system are oxidative stress, inflammation and cell-death. The applicability of an in vitro system with human lung cells as an instrument to evaluate possible biological effects of emissions of several indoor air sources (scented candles, hair and water resistant spray) created in a climate chamber was studied.
TNO Identifier
476245
ISBN
9781627482721
Source title
12th International Conference on Indoor Air Quality and Climate 2011, Austin, TX, USA, 5-10 June 2011
Pages
641-646
Files
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