On the combination of USEtox® and SimpleBox 4 Nano models for the derivatization of size-dependent characterization factors for engineered nanomaterials
article
Even if it has been claimed that Life Cycle Assessment is an
essential tool to analyze, evaluate, understand and manage the
environmental and health impacts of nanotechnology, few studies
incorporate characterization factors (CFs) for human toxicity and freshwater
ecotoxicity accounting for the impacts of engineered nanomaterials (ENMs)
beyond their manufacturing stage. The objective of the present work has
consisted in identifying the correspondence of the information required and
outputs provided by the USEtox® consensus model (which is not
nanospecific) and the SimpleBox4Nano model (which accounts for
nanospecific processes, e.g. aggregation, attachment and dissolution for Fate
Factor derivatization) in order to assess the possibility of integrating both to
derive size-dependent CFs for the varying sizes of ENMs throughout their
life cycle. The possibility to combine and integrate both models appeared to
be limited since there is no absolute correspondence between the two of
them.
essential tool to analyze, evaluate, understand and manage the
environmental and health impacts of nanotechnology, few studies
incorporate characterization factors (CFs) for human toxicity and freshwater
ecotoxicity accounting for the impacts of engineered nanomaterials (ENMs)
beyond their manufacturing stage. The objective of the present work has
consisted in identifying the correspondence of the information required and
outputs provided by the USEtox® consensus model (which is not
nanospecific) and the SimpleBox4Nano model (which accounts for
nanospecific processes, e.g. aggregation, attachment and dissolution for Fate
Factor derivatization) in order to assess the possibility of integrating both to
derive size-dependent CFs for the varying sizes of ENMs throughout their
life cycle. The possibility to combine and integrate both models appeared to
be limited since there is no absolute correspondence between the two of
them.
Topics
TNO Identifier
979964
Source title
E3S Web of Conferences
Editor(s)
Albrecht,S.
Fischer, M.
Scagnetti, C.
Barkmeyer, M.
Braune, A.
Fischer, M.
Scagnetti, C.
Barkmeyer, M.
Braune, A.
Pages
1-7
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