Suitability of low-dose open food challenge data to supplement double-blind placebo-controlled data in generation of food allergen threshold dose distributions
article
Food allergen threshold dose distributions are used in food allergen risk assessment to determine the level of risk within a food-allergic population to a defined exposure amount of allergenic food protein and to help inform allergen risk management decisions. There has been a long-standing interest in determining threshold dose distributions for different food allergens from a research and a risk management perspective.1-3 More recently, allergen risk management programmes utilizing population threshold dose distributions to inform the decision-making process have been endorsed by multiple international stakeholder groups and national agencies.4-7 The interest shown by all stakeholders regarding this area of research had placed an emphasis on gathering as many data points, from as many foods, as possible to better inform allergen risk assessments and risk management.
TNO Identifier
946584
ISSN
09547894
Source
Clinical and Experimental Allergy, 51(1), pp. 151-154.
Pages
151-154
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