A review of dermal exposure determinants for the dermal Advanced Reach Tool (dART) tool
report
The development of a dermal exposure model is a challenge because of the complexity of dermal exposure processes on one hand, and the scarcity of good quality and contextually-rich dermal exposure measurements. Dermal exposure modelling is further complicated by the difficulty of measuring dermal exposure due to the lack of standardised methods (CEN/TR 2006). For example, three types of sampling systems are typically used, i.e. interception methods, removal techniques and direct assessment (in situ detection). Despite these challenges, important advancements in dermal exposure modelling have been achieved since the start of the millennium, including the Bayesian Exposure Assessment Tool (BEAT) for biocides, the RISKOFDERM models (Van Hemmen et al. 2003) and structured semi-quantitative method to assess dermal exposure for chemical and biological agents, i.e. DREAM.
TNO Identifier
843208
Collation
127 p.
Place of publication
Zeist