Drug transporters: kinetics and metabolism
other
Transporter proteins are embedded in plasma membranes and actively transport their substrates (drugs, food components or endogenous compounds) into or out of the cell. Transporters play a significant role in the absorption, distribution and excretion of drugs. Drug-transporter interactions can cause unwanted drug-drug or drug-food interactions resulting in either decreased efficacy or enhanced toxicity. In the broad
range of DMPK research of TNO , several methods are available to study active drug transport. These specific models can be very helpful in predicting potential
drug-drug interactions.
range of DMPK research of TNO , several methods are available to study active drug transport. These specific models can be very helpful in predicting potential
drug-drug interactions.
TNO Identifier
871586
Publisher
TNO
Collation
2 p.
Place of publication
Zeist