Quantitative protein abundance measurements: absolute quantification of plasma membrane measurements
other
Membrane embedded transporter proteins play an important role in the absorption, distribution and excretion of many drugs. A reliable prediction of human pharmacokinetics of (new) drugs based on PBPK modeling is highly dependent on accurate determination of the absolute protein expression levels of these transmembrane transporter proteins.
TNO Identifier
871582
Publisher
TNO
Collation
2 p.
Place of publication
Zeist