Simultaneous identification of multiple β-lactamases in Acinetobacter baumannii in relation to carbapenem and ceftazidime resistance, using liquid chromatography-tandem mass spectrometry
article
Shotgun proteomics using liquid chromatography-tandem mass spectrometry (LC-MS/MS) was applied to detect β-lactamases in clinical Acinetobacter baumannii isolates. The correlation of the detection of β-lactamase proteins (rather than PCR detection of the corresponding genes) with the resistance phenotypes demonstrated an added value for LC-MS/MS in antimicrobial susceptibility testing. Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Topics
TNO Identifier
525581
ISSN
0095-1137
Source
Journal of Clinical Microbiology, 53(6), pp. 1927-1930.
Publisher
American Society for Microbiology
Pages
1927-1930
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