An improved method for the detection of α2-antiplasmin activity on the automated coagulation analyzer MLA Electra 1000C

article


Meijer, P.

Westerveld, W.

Huisman, L.G.M.
Comparison of the results for α2-antiplasmin activity of plasma samples (n = 61, range 0-125%) obtained by the 'immediate plasmin inhibition test' (IPIT) and by the automated method for the MLA Electra 1000C of Dade® shows a good correlation (R = 0.935) but a systematic disagreement especially relevant in the range below 40%. An improved method for the detection of α2-antiplasmin activity on the automated coagulation analyzer MLA Electra 1000C was developed. A linear calibration curve up to 150% was observed. A dilution curve of normal pooled plasma with plasma of an α2-antiplasmin deficient patient shows a linear curve (y = x + 7).
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α2-antiplasminautomated methodplasminalpha 2 antiplasminplasminassayautoanalyzerautomationconference papercontrolled studyfibrinolysishumanmajor clinical studyplasma
TNO Identifier
232684
Repository link
https://resolver.tno.nl/uuid:78c7fe5e-28a8-4453-afcf-410153bcc753
ISSN
02689499
Source
Fibrinolysis, 8(SUPPL. 2), pp. 160-162.
Pages
160-162
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