On-chip microreactor system for the production of nano-emulsion loaded liposomes: towards targeted delivery of lipophilic drugs
conference paper
An on-chip microreactor system for the production of novel nano-biodevices is presented. This nano-biodevice consists of a nano-emulsion loaded with lipophilic drugs, entrapped in liposomes. These nano-biodevices can be equipped with targeting molecules for higher drug efficiency. The microreactor system enables efficient production of the complicated nano-biodevices. We used the anti-inflammatory drug celecoxib dissolved in fish oil for the nanoemulsion. The nano-emulsion is stabilized with a surfactant dissolved in water. The microreactor provides great flexibility, and therefore the nano-biodevices can be produced at an appropriate location and can be customized for the patient.
TNO Identifier
462040
Article nr.
0013
Source title
6th International Conference on Microtechnologies in Medicine and Technology (MMB), Lucerne, Switzerland, May 4-6, 2011
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