Thrombolytic properties in a rabbit jugular vein thrombosis model of a tissue-type plasminogen activator mutant lacking the growth factor- and kringle 1-domains

Emeis, J.J.; Verheijen, J.H.

Thrombolytic properties in a rabbit jugular vein thrombosis model of a tissue-type plasminogen activator mutant lacking the growth factor- and kringle 1-domains

article

1992

Emeis, J.J.

Verheijen, J.H.

Chemicals/CAS: Recombinant Proteins; Tissue Plasminogen Activator, EC 3.4.21.68

Topics

Alpha 2 antiplasmin Alteplase Fk 2p Gowth factor Plasminogen Unclassified drug Animal experiment Animal model Blood clot lysis Conference paper Dose response Dose time effect relation Drug efficacy Fibrinogen blood level Intravenous drug administration Mutant Nonhuman Protein domain Spectrophotometry Vein thrombosis Animal Comparative Study Fibrinolysis Infusions, Intravenous Injections, Intravenous Jugular Veins Metabolic Clearance Rate Rabbits Recombinant Proteins Thrombosis Tissue Plasminogen Activator Animalia Oryctolagus cuniculus

TNO Identifier

232009

Repository link

https://resolver.tno.nl/uuid:36d1db1d-a32a-4cfe-b61d-976e4367a3fb

ISSN

00778923

Source

Annals of the New York Academy of Sciences, 667, pp. 421-423.

Pages

421-423

Files

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Thrombolytic properties in a rabbit jugular vein thrombosis model of a tissue-type plasminogen activator mutant lacking the growth factor- and kringle 1-domains

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