Plasmin inhibitory effect of rat tissues: Comparison with antiplasmin activity of plasma

article


Padro, T.

Hoogen, C.M. van den

Emeis, J.J.
Plasmin inhibition by rat tissue extracts were compared with rat plasma plasmin inhibition. Nine different tissues were extracted with an acid acetate-buffer (lung, heart, brain, adrenal, aorta, skeletal muscle, spleen and liver) or with KSCN-buffer (kidney), and antiplasmin activity was evaluated by a spectrophotometric method. All tissue extracts inhibited plasmin dose-dependently; the amount of plasmin inhibited by a fixed amount of extract depended upon the tissue. In rat plasma, antiplasmin activity was acid-labile, but acid treatment did not affect the plasmin inhibitory effect of tissues extracts. Chemicals/CAS: antiplasmin, 9049-68-7; plasmin, 9001-90-5, 9004-09-5; Antiplasmin; Plasmin, EC 3.4.21.7; Tissue Extracts
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AnimalAntiplasminComparative StudyHydrogen-Ion ConcentrationPlasminRatsRats, Inbred StrainsSupport, Non-U.S. Gov'tTissue Extracts
TNO Identifier
231634
Repository link
https://resolver.tno.nl/uuid:1bb57c0b-c61d-4d6a-a8f1-8e1b7aab7f2d
ISSN
00365513
Source
Scandinavian Journal of Clinical and Laboratory Investigation, 51(7), pp. 599-603.
Pages
599-603
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