Determination of progesterone by liquid chromatography - mass spectrometry using a moving-belt interface and isotope dilution

article



Greef, J. van der

Tas, A.C.

Rijk, M.A.H.

Noever de Brauw, M.C. ten
Progesterone can be determined rapidly and accurately with the method presented, using isotope dilution LC-MS with a moving-belt interface. Deactivation is very useful in that it minimizes belt memory effects and optimizes belt desorption characteristics. Since the moving-belt properties were found to change during time with respect to the parameters mentioned, isotope dilution is of importance in order to obtain accurate results. Chemicals/CAS: progesterone, 57-83-0; Progesterone, 57-83-0.
Topics


















ProgesteroneDrug analysisDrug determinationLiquid chromatographyMass spectrometryMethodologyNonhumanPreliminary communicationPriority journalProgesterone c 13SerumTheoretical studyChromatography, LiquidFreeze DryingHumanIndicator Dilution TechniquesProgesteroneRadioimmunoassaySpectrum Analysis, Mass
TNO Identifier
230006
Repository link
https://resolver.tno.nl/uuid:aaf41558-b1f1-4040-a84a-73a404448b03
Source
Journal of Chromatography - Biomedical Applications, 343(2), pp. 397-401.
Pages
397-401
Files
To receive the publication files, please send an e-mail request to TNO Repository.