Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified d-phenylalanine residues

article










Knaap, M. van der

Engels, E.

Busscher, H.J.

Otero, J.M.

Llamas-Saiz, A.L.

Raaij, M.J. van

Mars-Groenendijk, R.H.

Noort, D.

Marel, G.A. van der

Overkleeft, H.S.

Overhand, M.
The synthesis of new analogues of the cationic antimicrobial peptide gramicidin S, having a modified d-phenylalanine residue, their antibacterial properties against several Gram positive and negative strains, as well as their hemolytic activity is reported. © 2009 Elsevier Ltd. All rights reserved.
Topics


Anti-microbial peptidesBiological profileGramicidin S derivatives
TNO Identifier
241723
Repository link
https://resolver.tno.nl/uuid:5d25d033-2a5e-4ae3-ba25-7a7f6b007713
ISSN
0968-0896
Source
Bioorganic and Medicinal Chemistry, 17(17), pp. 6318-6328.
Pages
6318-6328
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