Absence of antigens related to murine mammary tumour virus polypeptides in rat mammary tumours

article



Bentvelzen, P.

Westenbrink, F.

Broerse, J.J.

Zwieten, M.J. van
Fifty-two rat mammary tumours were tested by radioimmunoassay for the presence of antigens related to the envelope glycoprotein gp52 and core protein p28 of the murine mammary tumour virus and found to be negative. The tumours assayed were from WAG/Rij (16 cases), BN/BiRij (16 cases) and Sprague-Dawley (20 cases) rats. Thirty of the rats had been irradiated with fast neutrons, 16 with X-rays, one had been implanted with a 17-??-oestradiol pellet and 5 were untreated. The tumours studied included 22 fibroadenomas, 2 adenomas, 19 adenocarcinomas, 4 sarcomas, 1 carcinosarcoma, and 4 of undetermined type.
Chemicals/CAS: Antigens, Viral; Peptides; Viral Proteins
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Animal experimentBreastBreast cancerMouseMouse mammary tumor oncovirusOncovirinaeAnimalAntigens, ViralFemaleMammary Neoplasms, ExperimentalMammary Tumor Virus, MousePeptidesRadioimmunoassayRatsRats, Inbred StrainsSupport, U.S. Gov't, P.H.S.Viral Proteins
TNO Identifier
229040
Repository link
https://resolver.tno.nl/uuid:b6432897-91d9-4607-a803-f9e088562f3d
ISSN
02775379
Source
European Journal of Cancer and Clinical Oncology, 17(4), pp. 407-410.
Pages
407-410
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