Cardiovascular effects of road traffic noise with adjustment for air pollution
conference paper
This study investigates cardiovascular effects of road traffic noise, accounting for air
pollution. Noise and particulate matter (PM10) exposure was assessed for the City of
Groningen sample (N = 40 856), and a selection of subjects that next visited the outpatient
clinic (PREVEND cohort; N = 8 592). Questionnaires and, for the cohort, measurements
(e.g. systolic and diastolic blood pressure, BMI, cholesterol) provided cardiovascular
endpoints, risk factors and confounders. For individual exposure assessment detailed
spatial data (e.g traffic characteristics, buildings, screening objects) were used together
with geographical information systems (GIS) and state-of-the-art modeling techniques.
Road traffic noise was associated with antihypertensive medication use in the City of
Groningen sample (unadjusted OR = 1.31 per 10 dB increase Lden). Adjusted odds ratios
were significant for the 45-55 yr age group in the full model adjusted for PM10 (OR =
1.19), and adjusted odds ratios were significant for higher exposure (Lden > 55 dB; OR=
1.21; with adjustment for PM10 OR = 1.31). In the cohort the unadjusted odds ratio was
1.35 for hypertension. The adjusted odds ratio was again significant for the 45-55 yr age
group.
pollution. Noise and particulate matter (PM10) exposure was assessed for the City of
Groningen sample (N = 40 856), and a selection of subjects that next visited the outpatient
clinic (PREVEND cohort; N = 8 592). Questionnaires and, for the cohort, measurements
(e.g. systolic and diastolic blood pressure, BMI, cholesterol) provided cardiovascular
endpoints, risk factors and confounders. For individual exposure assessment detailed
spatial data (e.g traffic characteristics, buildings, screening objects) were used together
with geographical information systems (GIS) and state-of-the-art modeling techniques.
Road traffic noise was associated with antihypertensive medication use in the City of
Groningen sample (unadjusted OR = 1.31 per 10 dB increase Lden). Adjusted odds ratios
were significant for the 45-55 yr age group in the full model adjusted for PM10 (OR =
1.19), and adjusted odds ratios were significant for higher exposure (Lden > 55 dB; OR=
1.21; with adjustment for PM10 OR = 1.31). In the cohort the unadjusted odds ratio was
1.35 for hypertension. The adjusted odds ratio was again significant for the 45-55 yr age
group.
TNO Identifier
470282
Source title
Inter-Noise 2007 - Noise and Sustainability Istanbul, Turkye, August 28-31, 2007
Pages
3428-3434
Files
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