Biomonitoring of exposure to permethrin based on adducts to proteins
conference paper
Although the insecticide permethrin is generally considered as a rather safe compound, a number of adverse effects have been reported. Consequently, biomonitoring of exposure to permethrin is important in order to minimize health risks. We here present the first steps towards the development of a novel methodology to assess the cumulative internal dose of exposure to permethrin, which is based on our observation that (reactive) glucuronide conjugates of permethrin metabolites form persistent adducts to albumin.
TNO Identifier
445655
Source title
HFM-149 Symposium 'Defense against the Effects of Chemical Hazards: Toxicology, Diagnosis and Medical Countermeasures', Edinburgh, Scotland (GBR), 8-10 October 2007
Collation
10 (Paper 24)