Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study

article



Brandt, P.A. van den

Smits, K.M.

Goldbohm, R.A.

Weijenberg, M.P.
Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake (P-trend, 0.05 and 0.02, respectively). Although an overall protective effect was not afforded, our results suggest an effect of magnesium in overweight subjects, possibly through decreasing insulin resistance. © 2007 Cancer Research.
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Food and Chemical Risk AnalysisBMICohort studiesColorectal cancerAdultAscending colonCancer riskCohort analysisInsulin resistanceMagnesium intakeMajor clinical studyMineral intakeNetherlandsObesityStatistical analysisStatistical significanceAgedBody Mass IndexCohort StudiesColorectal NeoplasmsFemaleHumansInsulin ResistanceMagnesiumMaleMiddle AgedNetherlands
TNO Identifier
239851
Repository link
https://resolver.tno.nl/uuid:79f42d62-1f9f-4bc1-8b4f-7e65c9ff95d2
ISSN
00070920
Source
British Journal of Cancer, 96(3), pp. 510-513.
Pages
510-513
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