Fusion of mass spectrometry-based metabolomics data

article




Smilde, A.K.

Werf, M.J. van der

Bijlsma, S.

Werff-van der Vat, B.J.C. van der

Jellema, R.H.
A general method is presented for combining mass spectrometry-based metabolomics data. Such data are becoming more and more abundant, and proper tools for fusing these types of data sets are needed. Fusion of metabolomics data leads to a comprehensive view on the metabolome of an organism or biological system. The ideas presented draw upon established techniques in data analysis. Hence, they are also widely applicable to other types of X-omics data provided there is a proper pretreatment of the data. These issues are discussed using a real-life metabolomics data set from a microbial fermentation process. © 2005 American Chemical Society.
Topics























Biomedical ResearchData reductionFermentationMass spectrometryMicrobiologyData setsMetabolomics dataMicrobial fermentationMetabolismAnalytic methodCell fusionData analysisFermentation techniqueMass spectrometryMetabolomicsPhase separationProteomicsStrain differenceTechniqueTranscriptomicsDatabasesEscherichia coliImage Processing, Computer-AssistedMass Spectrometry
TNO Identifier
238760
Repository link
https://resolver.tno.nl/uuid:ed9558e6-b00f-493e-a187-4d2039ed51f4
ISSN
0003-2700
Source
Analytical Chemistry, 77(20), pp. 6729-6736.
Pages
6729-6736
Files
To receive the publication files, please send an e-mail request to TNO Repository.