Presence and metabolism of the anabolic steroid boldenone in various animal species: A review
article
The review summarizes current knowledge on the possible illegal use of the anabolic steroid boldenone. The presence of boldenone and metabolites in different animal species and the possibility of the occurrence of endogenous boldenone and metabolites is assessed, as are the methods of analysis used for detection. Different laboratories in the European Union have examined the occurrence of boldenone and its metabolites. The results were discussed at different meetings of a European Commission DG-SANCO Working Party and summarized in an expert report. The situation of the different laboratories at this time is also covered herein. The overall conclusion of the Working Party was that there was a necessity for further research to distinguish between naturally occurring and illegally used boldenone forms. The confirmation of the presence of boldenone metabolites (free and conjugated forms) in certain matrices of animals is proposed as a marker for the illegal treatment with boldenone. © 2004 Taylor & Francis Ltd.
Topics
BiotechnologyAnabolic steroidsBoldenoneBovineCalvesEndogenousIllegal treatmentMetabolismPhytosterol17alpha boldenone17beta boldenoneAnabolic agentBoldenoneClostebolIllicit drugNandroloneStanozololTestosteroneUnclassified drugAnalytic methodCarcinogenicityChemical structureConjugationControlled studyCrustaceaDrug useEuropean UnionFeces analysisFemaleGas chromatographyHumanLaboratory testLiquid chromatographyMaleMass spectrometryMedical researchMicroorganismMycobacteriumNonhumanPhycomycetesPriority journalReviewScreening testSpecies differenceSteroid metabolismUrinary excretionAnabolic AgentsAnimalsFemaleHumansMaleSubstance Abuse DetectionTestosteroneAnimaliaBovinae
TNO Identifier
237774
ISSN
0265-203X
Source
Food Additives and Contaminants, 21(6), pp. 515-525.
Pages
515-525
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