Detection of biological aerosols by MALDI on-line aerosol TOF MS
conference paper
Matrix-assisted laser desorption/ionisation (MALDI) mass spectra were obtained from single biological aerosol particles using an aerosol time-of-flight mass spectrometer (ATOFMS). The inlet to the ATOFMS was coupled with an evaporation/condensation flow cell that allowed the aerosol to be coated with matrix material as the sampled stream entered the spectrometer. Mass spectra were generated from aerosols of gramicidin-S, erythromycin, insulin and cytochrome c, or of Bacillus subtilis var niger spores.
The results give a proof of principle that MALDI ATOFMS can provide nearly real-time identification of biological aerosols.
The results give a proof of principle that MALDI ATOFMS can provide nearly real-time identification of biological aerosols.
TNO Identifier
956436
Source title
2001 Scientific Conference on Chemical & Biological Defense Research, Hunt Valley, Maryland, USA, 6-8 March 2001
Collation
2 p.
Place of publication
Rijswijk
Files
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