Salinomycin-induced polyneuropathy in cats: Morphologic and epidemiologic data

article






Linde-Sipman, J.S. van der

Inch, T.S.G.A.M. van den

Nes, J.J. van

Verhagen, H.

Kersten, J.G.T.M.

Beynen, A.C.

Plekkringa, R.
In April 1996, an outbreak of toxic polyneuropathy in cats occurred in the Netherlands. All cats had been fed one of two brands of dry cat food from one manufacturer. Chemical analyses of these foods, stomach contents, and liver and kidney of affected cats revealed contamination with the ionophor salinomycin. Epidemiologic and clinical data were collected from 823 cats, or about 1% of the cats at risk. In 21 affected cats, postmortem examination was performed. The affected cats had acute onset of lameness and paralysis of the hindlimbs followed by the forelimbs. Clinical and pathologic examination indicated a distal polyneuropathy involving both the sensory at motor nerves.
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CatPeripheral nervous systemPolyneuropathySalinomycinToxicSalinomycinAnimal cellAnimal foodAnimal lamenessFood analysisFood contaminationMotor nerveNerve degenerationNonhumanParalysisPeripheral nervePolyneuropathySensory nerveAnimal FeedAnimalsCat DiseasesCatsCoccidiostatsDisease OutbreaksFemaleFood ContaminationForelimbHindlimbIonophoresLameness, AnimalMaleNetherlandsPeripheral NervesPeripheral Nervous System DiseasesPyrans
TNO Identifier
235328
Repository link
https://resolver.tno.nl/uuid:277eea7d-8755-48a1-858c-5727d967c488
ISSN
03009858
Source
Veterinary Pathology, 36(2), pp. 152-156.
Pages
152-156
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