Semi-continuous high speed gas analysis of generated vapors of chemical warfare agents
article
A method is presented for the continuous analysis of generated vapors of the nerve agents soman and satin and the blistering agent sulfur mustard. By using a gas sampling valve and a very short (15 cm) column connected to an on-column injector with a 'standard length' column, the system can either be calibrated or used for performing high speed gas analyses. When using a flame ionization detector, the detection limit was ca. 100 ppb (ca. 0.5-1.0 mg/m3). This technique is applied in inhalation toxicokinetic studies of nerve agents and mustard gas in the guinea pig.
Topics
AutomationData acquisitionNerve agentsSulfur mustardValve injectionVapor analysisMustard gasNerve gasNeurotoxinSarinSomanAnalytic methodAnimal experimentArticleAutoanalysisChemical warfareChromatographyGas analysisGas chromatographyGuinea pigNeurotoxicityNonhumanToxicokineticsVaporMustard gas, 505-60-2Neurotoxin, 39386-17-9Sarin, 107-44-8Soman, 96-64-0
TNO Identifier
234882
ISSN
0935-6304
Source
HRC Journal of High Resolution Chromatography, 22(3), pp. 153-158.
Pages
153-158
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