Effect of lutein on beta-carotene absorption and cleavage

article
Berg, H. van den
Carotenoid interactions during absorption anti in postabsorptive metabolism have been observed in both human and animal studies. We reviewed the mutual interactions reported between lutein and β-carotene and report new data on the postprandial β-carotene and retinyl ester response in the triglyceride-rich plasma lipoprotein (TRL) fraction in volunteers after a single test meal with β-carotene alone, or β-carotene combined with lutein or lycopene. Results indicate an inhibitory effect of lutein on β-carotene absorption, but apparently not on β-carotene cleavage. In a comparative study with two β-carotene/lutein ratios (2:1 and 1:2, respectively), this inhibitory effect of lutein was found to be most marked when lutein was the predominant carotenoid. In studies on plasma (serum) response also an inhibitory effect of β-carotene on lutein response was observed.
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β-CaroteneAbsorptionInteractionsLuteinBeta caroteneChylomicronDrug derivativeLipoproteinRetinolRetinol palmitateXanthophyllAbsorptionAnimalBloodConference paperDietDrug interactionHumanMetabolismAbsorptionAnimalsbeta CaroteneChylomicronsDietDrug InteractionsHumansLipoproteinsLuteinVitamin AAnimalia
TNO Identifier
234855
Repository link
https://resolver.tno.nl/uuid:b10fe470-010f-4643-a5d0-9b8c5dbaf2b6
ISSN
03009831
Source
International Journal for Vitamin and Nutrition Research, 68(6), pp. 360-365.
Pages
360-365
Files
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